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Estimates in 2024 for CNS stimulant use disorder and opioid use disorder include data from a small number of respondents (fewer than 10 each) who reported in a later section of the interview that they used methamphetamine with a needle in the past 12 months or that they smoked, sniffed, or used heroin with a needle in the past year despite having previously reported that they last used these substances more than 12 months ago

In conclusion, while caffeine and nicotine have some similarities in their effects on the brain and body, they also have many differences

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