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Fierce competition from Last Crusade , Lethal Weapon 2 and Batman contributed to the lacklustre box office of Licence to Kill that did for Timothy Dalton, along with the stronger violence - provoked by the Lethal Weapon and Die Hard franchises - that earned the Bond franchises first 15 certificate in the UK and PG-13 in the US
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Professor Elizabeth Sattely and her graduate student Warren Lau, of Stanford University, California, said podophyllotoxin, a chemical from Mayapple, is the natural precursor to etoposide, which is used in dozens of chemotherapy regimens for a variety of malignancies. The work, published in the journal Science, may lead to a more stable supply of the drug and allow scientists to make it even safer and more effective
