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One 2020 study looked at the effect of flavoured vs flavourless e-liquid on the growth of oral commensal streptococci and varied the nicotine content to make low nicotine concentration (5%) liquids and a high nicotine concentration (25%) liquids

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Banning various flavors of cigarettes and sponsorship at entertainment or sports events, and prohibiting free sampling of tobacco products and non-tobacco branded items are among the measures, which the study theorizes could explain why among high school students, from 2011 to 2016, the use of cigarettes, cigars and smokeless tobacco significantly decreased

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