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The relative mRNA expression of IL-8 was significantly higher in endothelial cells exposed to the combined treatment of tobacco smoke condensate and colchicine than in the controls and the endothelial cells treated with either tobacco smoke condensate or colchicine alone (Fig

[51] isolated bronchial tissue from patients with and without COPD, isolated and cultured goblet cells and promoted their differentiation and found that SAM-pointed domain-containing ETS transcription factor (SPDEF) and forkhead box protein A2 (FOXA2) had abnormal DNA methylation during goblet cell differentiation

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