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Standardization then requires conducting a series of blocks of regimented puffs (all with same puff duration and puff volume) varying different parameters to test the equilibrium between physical processes (figure 1) and considering the inter-parameter relations in figures 2-4

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For other trials, where quitting may not have started immediately, time quit can be derived from the study design details

as well as improve communication about the responsibilities of parents, teachers, and adults in protecting children from the harmful effects of tobacco