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Treatment should be based on the severity of nicotine dependence, the probability of developing withdrawal symptoms, risk of relapse, comorbidities, local resources, and patient preferences

Yet, in mice studies, researchers found THC also binds with receptors in the blood vessels, suggesting that THC could inflame the blood vessels in the same manner, causing inflammation and heart damage

However, these levels were much higher compared to cigarette users, which could be explained by longer hookah sessions with a higher puff number/volume [23, 75]

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