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Many of these sales can be attributed to an oral nicotine pouch brand called Zyn: research published in Substance Use and Addiction found that Zyn led the overall unit share among brands in the United States from 2019 to 2022, a time when unit sales of oral nicotine pouches increased more than six-fold from 126.06 million units from August to December 2019 to 808.14 million units from January to March 2022