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A 1-month exposure study investigated the impact of IQOS on rat ultrastructural lung airways and found that IQOS exposure led to a severe remodeling of smaller and larger airways, increased tissue ROS, and promoted oxidative DNA damage

Our assessment of these algorithms in the i2b2 notes was useful for showing the potential of this pipeline but cannot be considered a definitive finding

Factor loading ranged from 0.53 to 0.85 for the first factor (active communication) and 0.79 to 0.94 for the second factor (internalized perception of communication)

Strong recommendation, high certainty Recommendation 14 Nortriptyline should be considered as a second-line pharmacotherapy agent because of its adverse effects profile