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"But how you respond to and cope with your recurrent panic attacks can lead to other serious behavioral health disorders." You may develop health problems such as: Agoraphobia (fear of open or public spaces) Anxiety disorders Bipolar disorder Depression Heart disease Irritable bowel syndrome Lung problems Posttraumatic stress disorder Obsessive-compulsive disorder Substance abuse Thyroid problems "Problematic coping mechanisms such as refusing to leave the home and using alcohol, cannabis, or other substances to prevent or cope with panic attacks can lead to social isolation, depression, and substance use disorders," says Sylvester

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