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Although the effects of smoking are not the same as those of nicotine, there is clinical evidence that suggests that nicotine and/or its metabolites, such as cotinine, are responsible for the beneficial effect of smoking in patients with active UC

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Founded by entrepreneurs James Monsees and Adam Bowen, who met while studying at Stanford, Juul was blamed for igniting a rise in teen vaping through its youthful marketing campaigns and fruity flavors