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Reubens had nothing but praise for Tim Burton, the director of his cult classic movie, "Pee-Wee's Big Adventure." Only about 26 at the time (but looking like he was 12), Burton was personally selected by Reubens because of his obvious talent with art direction

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While the lack of THR support from some public health bodies and regulators is an admittedly muddied situation, the actual solution is crystal clear: science not politics is king and it is data that needs to inform and drive future regulatory leadership, discourse and direction