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Indeed, we found a decrease in LV%FS, LVEF, and VCF coupled with ultrastructural abnormalities indicative of cardiomyopathy in mice treated with e-cigarette (2.4% nicotine) compared to e-cigarette (0% nicotine) or saline exposed mice (198)

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Earlier devices use a heating blade that penetrates the tobacco stick, while newer platforms such as IQOS ILUMA use an induction-based heating system that eliminates the blade entirely