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Int J Mol (2018) 19:3605

If the patient is already using medicines to support smoking cessation, a pragmatic approach could be: If only a few days (to a week) has passed since they relapsed, it may be appropriate to continue with the remaining weeks of the treatment course If the relapse is longer (several weeks or more), or the patient is considered high risk for future relapses, restarting the treatment course from the beginning might be more beneficial to support the quit attempt (assuming the duration of treatment has not already been extended previously)

Electrocardiographic changes associated with smoking and smoking cessation: outcomes from a randomized controlled trial

He did it cold turkey, without nicotine gum, patches, or medication that many people use to wean themselves off tobacco