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The same pattern held up in smokers. DNA damage to oral epithelial cells, which line the mouth, is an early change that is associated with an increased risk for many types of chronic disease, including cancer and inflammatory diseases

The answer is simple: Even leaving aside our duty to investors and the fact that some major markets dont legally allow us to sell smoke-free nicotine products, the following two things would happen if PMI immediately stopped selling cigarettesboth of which would significantly impede our efforts to end smoking: Firstly, our adult consumers who smoke would switch to competitor brands

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In February, Attorney General Chris Koster announced a settlement allowing the state to recover the $50 million, but it depended on lawmakers passing legislation to close the loophole enjoyed by smaller tobacco companies that were not part of the original 1998 settlement