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make you wheeze and out of breath make you cough uncomfortably or painfully make your asthma worse if you have it There's been less research on it but smoking cannabis is likely to have many of the long term physical health risk as smoking tobacco (even if you don't mix the cannabis with tobacco)

Third, we only included published studies, and while the inclusion of unpublished studies may increase the likelihood of including lower quality work that has not been peer reviewed, it may also decrease publication bias, in which studies are only published if they have positive results

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In addition, it was uncertain to what extent participants complied with the study protocol by using the wPUM for every puff taken