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Prolonged exposure is associated with enhanced glycolysis, suppression of the tricarboxylic acid cycle and oxidative phosphorylation, mitochondrial dysfunction, and excessive production of mitochondrial reactive oxygen species

The decision was motivated by a desire "to preserve the pristine alpine environment our guests come here for," explained former Whistler Blackcomb CEO Dave Brownlie, when the new rule was announced in 2015

Facing plummeting demand with few alternative sources of jobs, areas dependent on primary sector industries such as mining and logging suffered the most

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