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A meta-analysis of three longitudinal studies from the UK has identified that ever e-cigarette users were six times more likely to take up tobacco smoking than never e-cigarette users, and there are similar findings from studies across Europe and North America 10,11

Nicotine gum is a popular NRT where nicotine content gets absorbed through the mouth's inner lining when chewed, triggering the release of pleasure-inducing dopamine and adrenaline