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The study did not look at biological differences in participants that might explain why those who quit smoking survived longer

In the research cited above, about 20 to 30 % of new vapers experience coughing at first

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It is difficult to say, but for those already addicted it seems most likely that reducing the effectiveness of nicotine delivery in this way would simply lead to smoking more cigarettes, just as lowering the nicotine content of cigarette tobacco does