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Nicotine MCAS and Histamine Intolerance Considerations Mast Cell Activation Syndrome (MCAS) and histamine intolerance frequently overlap with CIRS, adding another layer of complexity to symptom management

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p=0.984), and showed no significant differences depending on smoking duration, smoking intensity, and cumulative dose of smoking (Table 4)

We used independent t-test to calculate the continuous variables, such as the basic demographic data, with the variables presented as either mean SD or percent difference