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Hormonal changes due to menopause or other factors Side-effects of medications, especially those taken for hypertension Certain oral habits like bruxism, overuse of mouth-washes, overbrushing the tongue etc

For instance, the prefrontal cortex (PFC), the most critical neural network engaged in response inhibition and risk adjustment, continues to develop structurally and functionally into adulthood 20,22

and creating a national coordinating mechanism for tobacco control

PMIs cigarette market share has dropped sharply in countries like Italy (from 47.0% in FY2019 to 36.7% in FY2024), Japan (from 17.4% to 11.5%), and the Philippines (from 70.5% to 50.6%)