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HIFs are protective in the short-term, but chronic HIF stabilization in the RPE can exert detrimental effects [15,16,17,18], from which the metabolic shift is most relevant for the present study

Apart from this impact, researchers are saying further conclusions about possible problems are difficult to make due to a relative paucity of literature. The medical community seems confident they will find more links showing that cannabis smoke is unhealthy, but right now firm associations with cancer, chronic obstructive pulmonary disease (COPD), or emphysema like with tobacco have been elusive