That said, the lack of a filter can make cigar smoke feel far more intense even if it is not inhaled, and can be associated with an increase in tar intake and carcinogens
DISCUSSION To our knowledge, this is the first large-scale, longitudinal study to investigate the effect of smoking cessation on NODM risk among dyslipidemic patients
In future studies, it would be of considerable interest to understand how sustained smoking behaviour, driven initially by hedonic experience may further develop into dependence (i.e., psychological or physical craving for nicotine following withdraw), where habit-inducing regions such as the insula and striatum might eventually become involved 55,56
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