Early records of the plant being used for medical purposes date back to the Greek physician, botanist, and pharmacologist Pedanius Dioscorides, who wrote about the benefits of mullein leaf in De materia medica, or On Medical Material , a five-volume encyclopedia about medicine, including herbal remedies
Long-term Safety Data for NRT Users Data from many years shows that nicotine products are safer than tobacco
10.1111/j.1530-0277.2011.01443.x Alcohol
Every year, over a third of smokers attempt to quit, but only about 3% succeed ( Nicotine dependence can be defined as a pattern of psychological attributes that result in the compulsive and repetitive search for, and use of, nicotine (Kowiaski et al., 2018), which are certainly quite different from the euphoria or high typical of some other drugs of abuse