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The health and economic cost of tobacco According to WHO: The tobacco epidemic is one of the biggest public health threats the world has ever faced, responsible for over 7 million deaths annually, as well as disability and long-term suffering from tobacco-related diseases. Additionally, a study by the organisation found that approximately 80% of the 1.3 billion tobacco users worldwide live in low- and middle-income countries, where the burden of tobacco-related illness and deaths is heaviest