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In a review of nicotine pouch studies, human trialsall funded by pouch manufacturersshowed minimal damage to tooth enamel and reductions in preexisting oral lesions from other tobacco products

The CY 2010 final rule adopted the proposal, with minor adjustments based on public comments, and explained that these minor adjustments were in part due to non-response bias that results when the characteristics of survey respondents differ in meaningful ways, such as in the mix of practices sizes, from the general population (74 FR 61749 through 61750)

Avoid vaping and e-cigarettes as well as tobacco smoking

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