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Some populations bear a disproportionate burden. People with less than a high school diploma, those with low incomes, and those who experience mental illness are among the groups statistically more likely to smoke, according to CDC data

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State regulators attempting to address youth nicotine dependence and youth access to these products have faced increased difficulties, particularly because there are no nicotine concentration restrictions imposed by the FDA and nearly all new oral nicotine products are being marketed in an illegal fashion without FDA marketing authorization