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To accurately estimate the mean and standard error, we first estimated the uncertainty of individual concentrations through the regression parameter errors and residual variability, before combining these using inverse-variance weighting of the triplicates to yield a pooled mean and standard error

The above points notwithstanding, we agree with Sanders and Zijlmans that over-reliance on recourse to mystical-type effects as a means of measuring this particular aspect of psychedelic subjective effects has its limitations

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