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[44] Using this approach, the most important tumorigenic compounds in tobacco smoke were, in order of importance, acrolein, formaldehyde, acrylonitrile, 1,3-butadiene, cadmium, acetaldehyde, ethylene oxide, and isoprene

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Appeal for tobacco products can be conceptualized as willingness to try a product that is mediated by other factors such as abuse liability (e.g