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This failure of therapeutic action should not be compensated for by increasing the dose in smokers as this might result in the production of toxic, even potentially mutagenic estrogen metabolites - compounds recently associated with a higher risk of breast cancer

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Miller Professor of Communication at the Annenberg School, says that "these phrases and words can activate beliefs about the brand that are not specifically discussed in the ads themselves, ultimately misleading consumers." In the study, the researchers presented current and former smokers with a variety of NAS advertisements and then asked them to answer questions about NAS cigarettes