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discovered, in 1998, a positive association between PBD and alleles HLA-A11, HLA-B54, and HLA-Cw1, while HLA-A33 and HLA-B44 increased their frequencies in the control groups, suggesting a protective association for these alleles in Japanese populations 112

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[88] [89] Electoral defeat and resignation [edit] By 1969, the Labour Party was suffering serious electoral reverses, and by the turn of 1970 had lost a total of 16 seats in by-elections since the previous general election