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The effects of the patterning of the drinking on dimensions such as frequency of drinking occasions and whether there is heavy episodic drinkingor the magnitude of dose-response effects cannot, of course, be estimated from our aggregate analyses

Always follow the recommended dosage and usage guidelines provided by the manufacturer

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Cochrane Database of Systematic Reviews, 9 , CD010216 Kollins SH, English JS, Itchon-Ramos N, Chrisman AK, Dew R, O'Brien B, & McClernon FJ