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Although transdermal nicotine may be effective for UC, it has limited use due to its side effects such as acute pancreatitis, headache, and nausea (58)

This gives us a clue that there might be a connection, but randomized controlled studies would be the best way to discover whether semaglutide can actually help people quit smoking. The side effects of semaglutide are well understood and include: abdominal pain constipation diarrhea nausea and vomiting These could deter some people from using this drug to quit smoking