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Acute use can cause vasoconstriction, tachycardia, hypertension, hyperthermia, or seizures, while overdose may lead to stroke, heart attack, or sudden cardiac death

Arthritis Res Ther (2009) 11:R88

Conversely, the expression of asm_8.2128 and asm_20.1375 encoding two key enzymes in JA biosynthesis, lipoxygenase 6 (LOX6) and jasmonic acid O-methyltransferase (JMT), respectively, were strongly down-regulated in K326_R upon TMV treatment and were significantly lower compared to in K326 (Figure S2b)