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The main differences come down to how you use them, how much carbon they contain, and how they affect airflow

We recently showed that exposure of primary human bronchial epithelial cells (HBEC) to e-cig aerosols of 100% VG, in the absence of any nicotine or flavors, reduced the function of cystic fibrosis transmembrane conductance regulator (CFTR), an anion channel important for mucus hydration 19