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In addition, experiments where airway smooth muscle was pretreated with high concentrations of the purified aliphatic side chain of salmeterol failed to affect its long duration of salmeterol, which would have been expected to occur if anchored binding to an exosite was the primary mechanism responsible for its long duration of action (Bergendal A et al 1996)

Tobacco companies use advertising, concert promotions and other means to target Black communities and sell cigarette smoking as a lifestyle, she said

And the state needs to use resources to address its black-market problems