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The number would increase to 4.3 million by the end of the century

This change to a unit-based system was in response to the emergence in 2000 of low-priced cigarettes that had less tobacco content and less weight per cigarette and which, due to their price, were attracting young people to smoke and encouraging smokers to smoke more, as evidenced in a shift in consumer behavior pattern (sales of low-priced cigarettes increased from 6% in 2000 to 25% in 2003)

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This process delays the onset and can intensify and prolong effects as the liver converts THC into a more potent form known as 11-hydroxy-THC