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Mammen and Aethi proposed a revised Vicious Circle, suggesting that insults such as tobacco smoke impairs innate immune defenses, causing variations in the abundance, taxonomic composition and phylogenetic diversity of the lung microbiome

Kurmi Department of Medicine, McMaster University, Hamilton, Ontario, Canada Om P

This marks a fundamental shift: the policy goal is no longer simply to reduce smoking, but to limit nicotine dependence more broadly

Full-form air quality models are better able to capture these processes, but computational efficiency limits their geographic range and makes analyses of nationwide policies challenging