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[248] [249] On a 2009 episode of Inside the Actors Studio , he stated that ancestors from both sides of his family moved to America from Ireland starting in the 1850s, subsequently marrying only other Irish Catholics, and that his lineage is thus 100% Irish Catholic

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(c) Smoking and oxidative stress Oxidants and electrophiles arising from internal metabolism and xenobiotic sources play an important role in maintaining physiological functions, cell signaling and cellular defense mechanisms