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Yes, overdose is possible, though not common

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Inherited genetic syndromes that researchers are currently studying for their connection to pancreatic cancer, include: Hereditary breast cancer Hereditary ovarian cancer Familial atypical multiple mole melanoma (FAMMM) syndrome associated with skin and eye melanomas Lynch syndrome , also known as hereditary non-polyposis colorectal cancer (HNPCC) Peutz-Jeghers syndrome , also linked with polyps in the digestive tract and several other cancers Familial adenomatous polyposis (FAP) Researchers are also studying: Familial (hereditary) pancreatitis , usually caused by mutation in the PRSS1 gene but can also be caused by many other genes