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The substances in dip pouches, especially those containing nicotine, can have harmful effects on both the mother and the developing fetus or nursing infant

This may be due to the high affinity of tobacco for potassium, The up-regulation of K + transporter or K + channel related protein, and the up-regulation of K + transport growth defect inhibitory factor indicate that the root system needs better growth and development in an environment with high K + concentration

It is often printed with the brand logo or design and may include perforations for air ventilation

However, sites may be limited by organizational capacity to report back provider-level adoption and implementation metrics that may be useful for evaluation