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For example, a 2015 study published in The New England Journal of Medicine found that smokers who were assigned to use cigarettes with low nicotine content (between 0.4 and 2.4 milligrams of nicotine per gram of tobacco) smoked fewer cigarettes per day, and were less dependent on nicotine, than those who used regular cigarettes (with 15.8 milligrams of nicotine per gram of tobacco)

Sensitivity may develop, causing discomfort when brushing or consuming hot, cold, spicy, or acidic foods

Discover IQOS 3 DUO * 95% less represents the average reductions in levels of a range of harmful chemicals (excluding nicotine) compared to the smoke of a reference cigarette (3R4F)

Fans describe them as indulgent and exotic, a dessert smoke. Flavored Varieties and Regulations Flavored cigarettes once spanned fruit and dessert-inspired options, but many regions, including the U.S., have restrictions on flavor additives (except menthol)