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Treatment Treatment options for managing nicotine withdrawal include: Over-the-counter nicotine replacement therapies, such as the patch, gum, and lozenges, and nicotine replacement nasal sprays (available with a prescription) Prescription medicines like varenicline (Chantix) or bupropion (Wellbutrin XL) Online or in-person tobacco cessation programs Therapy and support groups Management Tips Distraction techniques can help take the edge off of unpleasant symptoms while waiting for cravings to pass

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