van gogh head of a skeleton with a burning cigarette 10 Facts about the Skull by Skeleton with Cigarette Art Glass

Nicotine is highly addictive and difficult to quit

CONFLICTS OF INTEREST The author has completed and submitted the ICMJE Form for Disclosure of Potential Conflicts of Interest and none was reported

Exclusion: Daily opioid users, allergic to or intolerant of either study drug, deemed unreliable for follow-up, or unlikely to return for crossover, pregnant or received an antiemetic, anticholinergic or antipsychotic agent intravenously (other than up to 100mg of dimenhydrinate) in the previous 24 hours

Clark wrote in an email that the higher minimum age for tobacco was consistent with the Greater Worcester Community Health Improvement Plan