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The throat hit is moderate at 3% and more pronounced at 5%, but neither strength produces the rough sensation that freebase nicotine devices are known for

The DSM-IV criteria for SUDs include separate criteria for dependence or abuse

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In assessing wording differences within mode for a web survey among young adults, McCabe et al.[18] found similar rates of substance use across surveys with equivalent wording, but significant differences in rates with minimal differences in question structure, such as adding dont know or refuse to the response categories or slightly altering a skip pattern