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What is interesting about this study is the authors utilized the saliva cotinine level-verified continuous abstinence rate (CAR) at weeks 4 to 12 as their primary efficacy endpoint (cotinine is a metabolite of nicotine and can be measured in saliva, urine, or blood to detect the use of nicotine and/or tobacco)

The price of a pack of cigarettes Increasing prices and adding tax measures on tobacco products has been used to decrease the demand for cigarettes

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Despite these limitations, our study provides significant evidence to support further prospective investigation into the relationship between poly-tobacco use and adverse birth outcomes