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For example, a recently published NHLBI-supported study suggests that just one vaping session -- even without nicotine -- can produce a negative response in the blood vessels of healthy nonsmokers

Additionally, the toxicity of nicotine and other substances depends on how the person smokes

Among unaffected first-degree relatives without RA followed prospectively, smoking was associated with inflammatory joint signs independent of genetics, CCP2, and other environmental factors

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