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It is critical to take action now to move toward ending tobacco and nicotine addiction because public health efforts to control tobacco have been insufficient to counter the tobacco industrys success in making their products appealing, highly visible, easy to access, and maintaining a favorable policy environment
The aim of our study was to investigate the molecular basis for effects of cigarette smoke extract (CSE) on the NLRP3 inflammasome, a component also activated by lipopolysaccharide (LPS)
Pack Years = # of packs smoked each day x # of years smoked For example, 2 packs per day for 10 years (2 x 10 =20) has 20 pack years of smoking, whereas pack a day for 20 years (1 x 20 = 20) also has 20 pack- years of smoking
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