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For instance, impulsive, uncontrolled behavior is seen in adults with orbitofrontal lesions [97] There is a relationship between dysfunction of the limbic system and irregularities in orbitofrontal cortex development

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[550] [551] [552] Barbara encouraged Sinatra to "fight" while attempts were made to stabilize him, and reported that Sinatra's final words were, "I'm losing." [553] His daughter, Tina, later wrote that she and her siblings had not been notified of their father's final hospitalization, and it was her belief that "the omission was deliberate

Notably, the increases in health beliefs from pictorial warnings were greatest for negative health effects that started with lower levels of prior beliefs about that health condition, such as gangrene and stroke (Ref