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de Rivas, B., Sampedro, C., Lpez-Fonseca, R., Gutirrez-Ortiz, M.., and Gutirrez-Ortiz, J.I., Appl

Nicotine stimulates receptors in the brain that release dopamine, creating a temporary sense of alertness or relaxation, depending on the user

Drug combination Regarding the efficacy of combination therapy, participants starting treatment with varenicline plus bupropion at baseline (n=21) were compared to those starting with varenicline at baseline and then adding bupropion at Week 4 (n=79), as well as to those starting treatment with bupropion and then adding varenicline at Week 4 (n=39)