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In September, the FDA reported that it has denied marketing authorization to over one million flavored ENDS products that lacked sufficient evidence that the benefit to adult smokers who used the flavor products would overcome the public health concern posed by the well-documented and considerable appeal of the products to youth.

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Although often perceived as safer than combustible cigarettes, mounting evidence confirms neurotoxic effects of nicotine in e-cig aerosols, and indicates that components other than nicotine can be detrimental to the developing brain